The objective of this investigation was to evaluate the efficacy and safety of purified Shilajit in moderately arthritic dogs. Ten client-owned dogs in a randomized double-blinded study received either a placebo or Shilajit (500 mg) twice daily for a period of five months. Dogs were evaluated each month for physical condition (body weight, body temperature, heart rate, and respiration rate) and pain associated with arthritis (overall pain, pain from limb manipulation, and pain after physical exertion).
NIH Funded Articles
- Objectively Coding Intervention Fidelity During A Phone-Based Obesity Prevention Study
- Wake-up Strokes Are Similar to Known-Onset Morning Strokes in Severity and Outcome
- Acculturation and Subclinical Atherosclerosis among U.S. South Asians: Findings from the MASALA study
- Predictors of Obstructive Sleep Apnea Risk among Blacks with Metabolic Syndrome
- Molecular Mechanism Linking BRCA1 Dysfunction to High Grade Serous Epithelial Ovarian Cancers with Peritoneal Permeability and Ascites
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Comparison of Two Freezing Extenders and their Influence on Sperm Quality of Tunisian Arab stallions
The objective of the study was to evaluate semen quality of Tunisian Arab stallions frozen with 2 methods using 2 freezing basedextenders: the INRA 96® or the INRA Freeze®.
Esophageal carcinoma is the eighth most common cancer, and the sixth most common cause of cancer-related deaths worldwide. Esophageal carcinomas in developing nations account for more than 80% of the total cases and deaths. Esophageal cancer can arise as esophageal squamous cell carcinoma (ESCC) or esophageal adenocarcinoma (EAC), which have distinct etiological and pathological characteristics. ESCC is the most common histological type of esophageal cancer in the Eastern world, and its incidence remains stable. In contrast, the epidemiology of esophageal cancer in developed nations has dramatically changed over the past 40 years. Forty years ago, ESCC accounted for more than 90% of esophageal cancer cases in the United States. However, adenocarcinoma has now become the leading type of esophageal cancer in the United States, representing 80% of cases.
Recent studies have supported a role for the proteolytic cleavage of apolipoprotein E4 (APOE4) as a potential mechanism for the enhanced dementia risk associated with Alzheimer’s disease. To determine whether APOE4 fragmentation is correlated with AD, ELISA assays were performed with cerebral spinal fluid (CSF) and plasma samples utilizing an antibody that specifically detects a 17 kDa amino-terminal fragment (p17) of APOE (nApoECF antibody). In CSF samples, levels of APOE fragmentation were minimal in both neuropathological normals (NPNs) and AD cases and there were no significant differences between the two cohorts across APOE genotypes.