Here in a systematic, accurate and reliable method, Head-Space Gas Chromatography-Mass Spectrometry (HS-GC/MS) was developed to determine blood carboxyhemoglobin (COHb%), in order to investigate deaths related to CO exposure especially involving blood and hepatic tissues.
NIH Funded Articles
- Acculturation and Subclinical Atherosclerosis among U.S. South Asians: Findings from the MASALA study
- Wake-up Strokes Are Similar to Known-Onset Morning Strokes in Severity and Outcome
- Objectively Coding Intervention Fidelity During A Phone-Based Obesity Prevention Study
- Predictors of Obstructive Sleep Apnea Risk among Blacks with Metabolic Syndrome
- Molecular Mechanism Linking BRCA1 Dysfunction to High Grade Serous Epithelial Ovarian Cancers with Peritoneal Permeability and Ascites
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Genetic Characterization and Sequence Variations in 12S rRNA of Mitochondrial Gene in Three Indian Civets (Viverridae) Species: Implication in Wildlife Forensics
Comparative genomics of 12S and 16S rRNAs, cytochrome b (Cyt b) and the control region (CR) of mtDNA genome are commonly used in phylogenetics and wildlife forensics. We document the genetic characteristics and sequence variations of 12S rRNA (384 bp) in Indian civets, viz., the common palm civet (Paradoxurus hermaphroditus) (n=9), small Indian civet (Viverricula indica) (n=7) and Himalayan palm civet (Paguma larvata) (n=5). The nucleotide compositions vary from 17.6% to 36.3%, and found one to two haplotypes in all three civet species. Observed sequence divergence was 0.001 to 0.002 and 0.057 to 0.110 within and between species respectively. The nucleotide diversity was 0.00102 to 0.00184. Tajima’s D value was negative (-0.097256 to -1.36240) but statistically non-significant in all three species. Based on genetic characteristics, we discuss the use of observed forensically informative nucleotide sequencing (FINS) and topology in species identification for forensic purposes among these three civet species.
Dyke Davidoff-Masson syndrome (DDMS) is a rare disease characterized by cerebral hemiatrophy due to brain insult in fetal life. Clinical symptoms include seizures, facial asymmetry, hemiplegia or hemiparesis, and mental retardation.
Development of the Analytical Model for the Assessment of the Efficiencies of Different Therapeutic Modalities in Leukemia
Different therapeutic regimes like chemotherapy, cytokine based immunotherapy and/or stem cell transplantation are generally be the suggested options for treatment of leukemia. However, the selection of the best therapeutic strategy for an individual patient remains uncertain till now